In vivo production of different chloroform metabolites: effect of phenobarbital and buthionine sulfoximine pretreatment.
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چکیده
منابع مشابه
In vivo production of different chloroform metabolites: effect of phenobarbital and buthionine sulfoximine pretreatment.
The regioselective attack on microsomal phospholipid (PL) polar heads (PH) and fatty acyl chains (FC) demonstrated in vitro has been exploited for the selective quantitation in vivo of the biochemical damages produced by the oxidation and reduction products of CHCl3 metabolism. Five hours after CHCl3 injection (60 mg/kg body weight, ip) to control Sprague-Dawley rats, most of the label covalent...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1994
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.94102s945